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Abuse Deterrent Opioids: A Survey of Physician Beliefs, Behaviors, and Psychology
The purpose of this project was to evaluate beliefs and behaviors pertaining to abuse-deterrent opioids (ADFs). Objective: The objective of our study was to assess physician experiences with prescribing ADF…
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Impacts of Initial Prescription Length and Prescribing Limits on Risk of Prolonged Postsurgical Opioid Use
In response to concerns about opioid addiction following surgery, many states have implemented laws capping the days supplied for initial postoperative prescriptions. However, few studies have examined changes in the…
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Drug Checking for Novel Insights into the Unregulated Drug Supply
Tobias et al. (Am J Epidemiol. 2022;191 (2):241–247) present a novel analysis of time trends in fentanyl concentrations in the unregulated drug supply in British Columbia, Canada. The preexisting knowledge…
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Research Led by People Who Use Drugs: Centering the Expertise of Lived Experience
Research collaborations between people who use drugs (PWUD) and researchers are largely underutilized, despite the long history of successful, community-led harm reduction interventions and growing health disparities experienced by PWUD.…
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Treatment Experiences for Skin and Soft Tissue Infections Among Participants of Syringe Service Programs in North Carolina
The objective of this study was to examine SSTI treatment experiences among people utilizing services from syringe services programs. Introduction: Bacterial and fungal infections, such as skin and soft tissue…
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Sociodemographic and Clinical Predictors of Prescription Opioid Use in a Longitudinal Community-Based Cohort Study of Middle-Aged and Older Adults
This work focuses on identifying factors associated with opioid use in middle-aged and older adults is a fundamental step in the mitigation of potentially unnecessary opioid consumption and opioid-related harms.…
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Trends in Drug Overdose Mortality Rates in Kentucky, 2019-2020
In April 2020, early signals from emergency medical services data raised concerns for increasing numbers of drug overdoses during the emerging COVID-19 pandemic in Kentucky.1 Subsequently, provisional national data for…
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Association Between Statewide Opioid Prescribing Interventions and Opioid Prescribing Patterns in North Carolina, 2006–2018
This work examines the impact of three sequential statewide policy and legislative interventions on opioid prescribing practices among privately insured individuals in North Carolina. Methods: An interrupted time series approach…
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Day-of-Surgery Gabapentinoids and Prolonged Opioid Use: A Retrospective Cohort Study of Medicare Patients Using Electronic Health Records
While preoperative gabapentinoids are commonly used in surgical multimodal analgesia protocols, little is known regarding the effects this therapy has on prolonged postsurgical opioid use. In this observational study, we…
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Four Definitional Variants Inhibit Clinical Interpretation of Morphine Equivalence
Morphine-standardized doses are used in clinical practice and research to account for molecular potency. Ninety milligrams of morphine equivalents (MME) per day are considered a “high dose” risk threshold in…
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